FDA Approves Non-Addictive Painkiller as Alternative to Opioids

The FDA has approved Journavx, a new pain medication from Vertex Pharmaceuticals, designed to provide pain relief without the addiction and overdose risks associated with opioids. The drug, intended for short-term pain following surgeries or injuries, marks the first major pharmaceutical breakthrough in pain management in over 20 years.

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Journavx works by blocking pain-signaling proteins before they reach the brain, differing from opioids, which activate receptors in the brain that can lead to addiction. While studies show it provides more relief than a placebo, its effectiveness is comparable to opioid-acetaminophen combinations.

The drug, however, comes at a higher price—$15.50 per pill, significantly more than generic opioids. While some experts see promise in its alternative approach, its modest results and high cost may limit widespread adoption.

Despite setbacks in studies on chronic pain, Vertex plans to continue testing Journavx for long-term pain management. The approval represents a potential turning point in the fight against opioid addiction, though its real-world impact remains to be seen.

Source: APNews